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What is the skin’s microbiome?

Functioning as the exterior interface of the human body with the environment, skin acts as a physical barrier to prevent the invasion of foreign pathogens while being inhabited by the commensal microbiota – a complex community of microbes including bacteria, fungi and viruses. These microorganisms and their surrounding environment are the microbiome.

The skin microbiome is tremendously diverse in organism number and activity. The composition of the microbiome depends on intrinsic factors: the body part as the skin of each body part exhibits different microbe compositions, and physiology of the skin, which is related to a microenvironment characterized by moisture, dryness, and sebaceous content. In addition, the skin microbiome undergoes temporal changes with age, and also varies with genetics and gender. Finally, the microbiome is influenced by extrinsic factors, such as diet, lifestyle, hygiene routine, geographical location, climate, living environment, antibiotic and cosmetics use.

The microbiome is essential for maintaining skin barrier function by participating in essential physiological processes that occur in the skin. The microbiome also interacts directly with pathogenic microorganisms encountered on the skin surface.

In particular, the microbiome participates in physical, chemical, microbial and both innate and adaptive immunological ways in performing skin barrier functions. These interrelationships are the product of a well-controlled and delicately balanced microbiome.

However, this balanced system can quickly become unstable from continuous exposure to various extrinsic and intrinsic factors, including pollution, sun damage and irritating skincare products.

Changes in the skin microbiome can lead to pathophysiological problems, inducing inflammatory skin conditions:

 

How can I improve my skin’s microbiome with skincare?

Balancing your skin’s microbiome takes a combination of prebiotic, probiotic and postbiotic ingredients. It’s important to find microbiome skincare that combines these three elements to increase results.

Here’s how the skin’s pro-, pre- and postbiotics work together to maintain the micrbiome’s balance:

When the microbiome is stable and healthy, you’ll see and feel the results on your skin:

Our serum The wonder complexion contains ingredients that protect the microbiome and strengthen skin barrier:

Glyceryl glucoside

Ceramides

Ceramides make up around 50% of lipids of the skin barrier and are essential for a healthy and hydrated skin barrier. And a strong skin barrier keeps the microbiome

balanced.

 

References:

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Byrd AL, Belkaid Y, Segre JA. The human skin microbiome. Nat Rev Microbiol. 2018

Mar;16(3):143-155.    doi:   10.1038/nrmicro.2017.157.   Epub   2018   Jan   15.   PMID:

29332945.

Eisenstein    M.    The    skin   microbiome.   Nature.   2020   Dec;588(7838):S209.    doi:

10.1038/d41586-020-03523-7. PMID: 33328671.

Flowers L, Grice EA. The Skin Microbiota: Balancing Risk and Reward. Cell Host

Microbe. 2020 Aug 12;28(2):190-200. doi: 10.1016/j.chom.2020.06.017. PMID: 32791112; PMCID: PMC7444652.

Lee HJ, Kim M. Skin Barrier Function and the Microbiome. Int J Mol Sci. 2022 Oct 28;23(21):13071. doi: 10.3390/ijms232113071. PMID: 36361857; PMCID: PMC9654002.

Luna PC. Skin Microbiome as Years Go By. Am J Clin Dermatol. 2020 Sep;21(Suppl 1):12-17. doi: 10.1007/s40257-020-00549-5. PMID: 32910437; PMCID: PMC7584528.

Sinha S, Lin G, Ferenczi K. The skin microbiome and the gut-skin axis. Clin Dermatol. 2021 Sep-Oct;39(5):829-839. doi: 10.1016/j.clindermatol.2021.08.021. Epub 2021 Sep 3. PMID: 34785010.

Smythe P, Wilkinson HN. The Skin Microbiome: Current Landscape and Future Opportunities. Int J Mol Sci. 2023 Feb 16;24(4):3950. doi: 10.3390/ijms24043950.

PMID: 36835363; PMCID: PMC9963692.

Swaney MH, Kalan LR. Living in Your Skin: Microbes, Molecules, and Mechanisms.

Infect Immun. 2021 Mar 17;89(4):e00695-20. doi: 10.1128/IAI.00695-20. PMID: 33468585; PMCID: PMC8090955.

Yang Y, Qu L, Mijakovic I, Wei Y. Advances in the human skin microbiota and its roles in cutaneous diseases. Microb Cell Fact. 2022 Aug 29;21(1):176. doi:

10.1186/s12934-022-01901-6. PMID: 36038876; PMCID: PMC9422115.

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